Corpus Curare Spiritumque
A new study shows that the vast majority of patients, the presence of advanced colorectal cancer, on the basis of other organs (stage IV), the transaction is not immediate, the primary tumor in the large intestine. Researchers from Memorial Sloan-Kettering Cancer Center (MSKCC), their data today in the American Society of Clinical Oncology Annual Meeting.
“For this population with metastatic disease who are not cured by the operation, the operation of the intestine is not always necessary,” said Philip Paty, a surgical oncologist at MSKCC and one of the study’s authors attribute. “When the tumor of the intestine is not the cause of obstruction, perforation or hemorrhage, we found that these patients the best treatment with chemotherapy. Live on the removal of chemotherapy, patients, the risk of complications and surgical treatment may for all sites of disease without delay. ”
For this retrospective study, a multidisciplinary team stare 233 cases, metastatic colorectal cancer treated MSKCC 2000 to 2006. Their analysis revealed that 217 of 233 patients, or 93%, no complications, the need for resection of primary tumor. Only 16 patients for the transaction management problem in two points.
Formerly, in the traditional approach in the treatment of stage IV disease, patients subjected to two points, immediately after their surgery for diagnosis and chemotherapy treatments usually start three to six weeks later. The grounds for the immediate resection was two points for the prevention of future problems and complications during the first tumor. It was estimated that the majority of bowel cancer have limited response to chemotherapy.
But with the development of better chemotherapy treatments over the past ten years, doctors and other MSKCC community oncology started in patients with stage IV disease, otherwise, and began to administer chemotherapy as initial treatment. These treatments seemed reliable because of two points both tumors and metastases, but it has not published data to support this approach.
“We now know that the systematic use of the operation in these patients is based on ancient thought, and we are beyond. It is increasingly the need for exceptions on the basis of the clinical situation, but our default position should not to operate, “said Dr. Paty.
Colorectal cancer is the fourth most common cancer and second leading cause of cancer deaths in the United States.
A new study shows that the vast majority of patients, the presence of advanced colorectal cancer, on the basis of other organs (stage IV), the transaction is not immediate, the primary tumor in the large intestine. Researchers from Memorial Sloan-Kettering Cancer Center (MSKCC), their data today in the American Society of Clinical Oncology Annual Meeting.
“For this population with metastatic disease who are not cured by the operation, the operation of the intestine is not always necessary,” said Philip Paty, a surgical oncologist at MSKCC and one of the study’s authors attribute. “When the tumor of the intestine is not the cause of obstruction, perforation or hemorrhage, we found that these patients the best treatment with chemotherapy. Live on the removal of chemotherapy, patients, the risk of complications and surgical treatment may for all sites of disease without delay. ”
For this retrospective study, a multidisciplinary team stare 233 cases, metastatic colorectal cancer treated MSKCC 2000 to 2006. Their analysis revealed that 217 of 233 patients, or 93%, no complications, the need for resection of primary tumor. Only 16 patients for the transaction management problem in two points.
Formerly, in the traditional approach in the treatment of stage IV disease, patients subjected to two points, immediately after their surgery for diagnosis and chemotherapy treatments usually start three to six weeks later. The grounds for the immediate resection was two points for the prevention of future problems and complications during the first tumor. It was estimated that the majority of bowel cancer have limited response to chemotherapy.
But with the development of better chemotherapy treatments over the past ten years, doctors and other MSKCC community oncology started in patients with stage IV disease, otherwise, and began to administer chemotherapy as initial treatment. These treatments seemed reliable because of two points both tumors and metastases, but it has not published data to support this approach.
“We now know that the systematic use of the operation in these patients is based on ancient thought, and we are beyond. It is increasingly the need for exceptions on the basis of the clinical situation, but our default position should not to operate, “said Dr. Paty.
Colorectal cancer is the fourth most common cancer and second leading cause of cancer deaths in the United States.
